Monday, August 31, 2009
World's first cloned wolf dies
Saturday, August 29, 2009
Tick saliva could hold cancer cure: Brazilian scientists
They have identified a protein in the saliva of a common South American tick, Amblyomma cajennense, that apparently reduces and can even eradicate cancerous cells while leaving healthy cells alone.
"This is a radical innovation," said Ana Marisa Chudzinski-Tavassi, the molecular biologist at the Instituto Butantan in Sao Paulo who is leading the research.
"The component of the saliva of this tick could be the cure for cancer," she told AFP.
She said she stumbled on the properties of the protein, called Factor X active, while testing the anti-coagulant properties of the tick's saliva -- the way it stops blood thickening and clotting so the tick can keep gorging itself on its host.
The protein shares some characteristics with a common anti-coagulant called TFPI (Tissue Factor Pathway Inhibitor), specifically a Kunitz-type inhibitor which also has been shown to interfere with cell growth.
A theory that the protein might have an effect on cancerous cells led to laboratory tests on cell cultures which exceeded all expectations.
"To our surprise it didn't kill normal cells, which were also tested," Chudzinski-Tavassi said. "But it did kill the tumorous cells that were being analyzed."
In her modest lab in the institute, housed in a rundown building, a line of immobile bloated ticks could be seen lined up with straws under their heads.
The small amounts of saliva captured that way was reproduced many times over in yeast vats so that tests could be carried out on lab rats with cancer.
The results have been more than promising.
"If I treat every day for 14 days an animal's tumor, a small tumor, this tumor doesn't develop -- it even regresses. The tumor mass shrinks. If I treat for 42 days, you totally eliminate the tumor," the scientist said.
Producing a medicine from the find, though, will require years of clinical tests and a significant financial investment neither of which Brazil is geared to provide.
Chudzinski-Tavassi has applied for a patent on the tick protein, and is presenting her team's discovery in medical journals and conferences around the world.
But she says moving beyond her lab "proof of concept" will be frustratingly difficult.
"To discover this is one thing. To turn it into a medicine is a whole other thing entirely," she said.
Monday, August 24, 2009
Beckham: Three sons are enough for me
Sunday, August 23, 2009
New York painter barks for art
Kruger begged for role with Tarantino
Tuesday, August 18, 2009
Lopez scared of dark
Sunday, August 16, 2009
Madonna turns 51 on concert stop in Poland
In a break between two songs, a fan held up a sign wishing her a happy birthday and audience members sang, "may you live a hundred years," a traditional Polish birthday song.
"I feel your love!" Madonna told the crowd of tens of thousands gathered on a large green field for the latest stop in her Sticky & Sweet tour.
Many of the fans near the stage also held up paper hearts. One said: "Adopt Me."
Her stop in Warsaw fell not only a day before her birthday, but also on the August 15, the Roman Catholic holiday celebrating the heavenly assumption of the Virgin Mary — timing that angered some Catholics.
Several people who objected to Madonna held up banners outside the concert venue, and a Catholic group tried to spearhead protests in past weeks hoping to force the Material Girl to change the date of the concert. It failed, however, to win support from the official church or the public. Though Poland, homeland of the late John Paul II, is mainly Catholic, young urban Poles have overwhelmingly embraced pop culture and mores.
During the concert, Madonna also paid tribute to Michael Jackson, who died in June.
A Jackson impersonator did the King of Pop's signature moonwalk dance move while wearing a sequined jacket, white T-shirt, white glove and white socks, while a large photograph of him as a boy appeared on stage.
"Let's give it up for one of the greatest artists the world has ever known," Madonna shouted, and then segued into a performance of her old hit "Holiday."
Thursday, August 13, 2009
Size of Aussie birds shrinking from global warming
Gaga dismisses hermaphrodite story
Lady Gaga is laughing off "ridiculous" rumours she has both male and female reproductive organs.Recent Internet footage of the Poker Face singer onstage has sparked fresh debate as to whether or not the hitmaker is a hermaphrodite - because a bulge can clearly be seen. And now gossip website HollyScoop.com reports Gaga actually addressed the rumours of her sexuality with a blog entry at Christmas (08). The website claims the singer wrote, "It's not something that I'm ashamed of, just isn't something that i go around telling everyone. Yes. I have both male and female genitalia, but i consider myself a female." However, the star's manager tells ABC News, "This is ridiculous."
Miley pines for ex-lover
yfriend Justin Gaston. The 'Hannah Montana' actress has left a series of heartfelt messages for her former partner - who she split from in June after around a year of dating - on social networking website Twitter, sparking speculation they may reunite.She wrote on Wednesday : "I am in between happy and sad today. I'm happy because I love you. I'm sad because I can't get enough of you."Earlier this week, the pair both confessed they were struggling to cope with the split by posting their innermost feelings on the internet.Underwear model Justin, 21, wrote: "Just recorded a demo.. Now I'm sitting on the couch wondering why we as humans try to pretend everything's okay when it isn't.. Just be real (sic)."Miley replied: "Everything IS ok. Honestly. I can't change you're mind and your heart no longer belongs to me. Maybe YOU'RE the one pretending you're fine (sic)."The 16-year-old star appeared to be dwelling on Justin's words, as she later wrote: "Why do I continue to torture myself?"Drifting away to a better place while listening to 'Comfortable'. This song makes me cry everytime... (sic)."
Tuesday, August 11, 2009
MJ's death reopens old memories for Elvis fans
"I said 'I can't believe it's happening again,'" Smith recalled. "It hurt, it really did. Even though I wasn't a Michael Jackson fan, I could feel the pain because it happened to somebody I had loved, and I know what his family and his fans were going through."
Smith, who is president of the Elvis Fever fan club in Jacksonville, Fla., and millions of others will remember the fallen icon Aug. 16, the day he was found dead in his home at age 42 in 1977, the victim of heart failure worsened by prescription drug abuse.
They are quick to offer advice to Jackson fans: Focus on the pop idol's music and generosity, not his shortcomings or the rumors about his death.
"Don't believe everything you hear and read," Smith warned. "Respect him for what you hear of his music and don't listen to the gossip."
Sandi Pichon of Slidell, La., who says she knew Presley personally and has written two books about him, "Raised on Elvis! Elvis! Elvis!" and "Elvis on Tour '75," says the pain will ease but never lift.
"Much like Elvis, once he touched your life you're never the same," Pichon said of Jackson. "The comfort they are going to find is listening to his music and relying on his memories and keeping the positive things alive."
Pichon will travel to Presley's Graceland mansion in Memphis for Elvis Week, a nine-day run of festivals and events that began Saturday.
If Presley is any guide, there will be a proliferation of Jackson fan clubs. Elvis Presley Enterprises, a corporate entity created by Presley's trust to run Graceland, recognizes more than 500 active fan clubs around the world.
"It's really nice to get together and reminisce — 'Did you see Elvis in concert?' 'What was it like?' 'I played this record until it was no more and I had to replace it,'" said Geri Vegher, president of Oklahoma Fans for Elvis. "It makes a difference to get together and talk things out and relive your memories. I'd tell Michael Jackson fans to be prepared to do that and to do it with gladness."
Fans say it also helps having Graceland, a bustling museum and tourist site with more than 600,000 people a year passing through its music-note encrusted gates. The 13.8-acre home and grounds include the singer's grave.
"I think it makes a difference," Vegher said. "I stand honor guard every year (at Graceland), and when people go up the hill to the grave site they're laughing, they're talking, they're reliving their memories. But when they come back down on the other side, they're sober, they're crying, they're very emotional."
The connections between Presley's Graceland and Jackson's Neverland ranch are strong. Presley's daughter, Lisa Marie, was once married to Jackson, and some of the same questions about the future of Neverland were raised about Graceland.
The Presley estate opened the property as a for-profit museum in 1982 to help pay for upkeep. Graceland has since become one of Memphis' top attractions.
"Elvis kind of set the bar for a lot of things, not just the music but even concert production and how security is done. I think beyond his death he's still setting the bar in terms of how to manage the estate and market him," said Jamie Coyne, founder and vice president of Elvis Extravaganza Fan Club in Columbus, Ohio, which bills itself as the largest Elvis fan club in the world with 164,000 members.
"If you take Elvis' grave away from Graceland and put it in a cemetery, you take away the moneymaking ability and the focal point for fans," Coyne said.
But others believe Presley and Jackson shared a magnetism and connection to their fans that transcends any physical place or structure.
"He could give you a grin that would melt your heart or make you believe you were the most special person in the world," Pichon said of Presley. "His love for his fans was reflected through his performance, and I think the same thing is true of Michael Jackson. People felt they were part of his life whether they knew him or not."
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Hudgens wants Efron to give party
Vanessa Hudgens wants Zac Efron to throw her a surprise birthday party. The 'High School Musical' star has been "dropping hints" about what she expects from her co-star and boyfriend Zac when she turns 21 in December.The young beauty said: "I'm hoping someone will throw me a big party. I'm just like, 'Someone throw me a party' because I haven't had a birthday party since I was like nine years old so I think it's about time."It's a great excuse. I was like, 'At 16 I'll have a party' and it never happened. Then I was like, '18, get a party!' Never happened. And so it better happen this year. I'm getting a party this year. I know it!"When it comes to birthday presents, Vanessa isn't fussy - as long as it's not an engagement ring.Even though the star has been dating Zac for around three years, she recently revealed she isn't ready to settle down.She said: "I think marriage and starting a family is great, but I'm so focused on my career right now that it doesn't really cross my mind."
Monday, August 10, 2009
Tiny deer among 350 new species found in Himalayas
But researchers warn that the effects of climate change, as well as development, threaten the diverse habitat that supports these species.
"This enormous cultural and biological diversity underscores the fragile nature of an environment which risks being lost forever unless the impacts of climate change are reversed," said Tariq Aziz, the leader of the World Wildlife Fund's Living Himalayas Initiative, a regional conservation program that covers India, Nepal and Bhutan.
The WWF is calling on the countries to develop a conservation plan for the region — which also includes parts of Myanmar and Tibet — and for governments to give local communities more authority to manage the forests, grasslands and wetlands.
The group found that almost three-quarters of the discoveries between 1998 and 2008 were plants, including 21 new orchid species. But it also listed 16 amphibians, 16 reptiles, 14 fish, two birds, two mammals and at least 60 new invertebrates. Most of the discoveries have already been reported in peer-reviewed, scientific journals.
Among the most exciting was the miniature muntjac, the world's smallest deer species — standing just 60-80 centimeters (25-30 inches) tall and weighing about 24 pounds (11 kilograms). Scientists at first believed the animal found in northern Myanmar was a juvenile of another species, but DNA tests confirmed it was distinct.
Scientists also found Rhacophorus suffry, a bright green frog in northeast India that uses its long, webbed feet to glide in the air. They also discovered two chocolate-brown catfish from Nepal that have evolved unique adhesive undersides to stick to rocks in fast-moving streams.
"It is astonishing to observe that a large number of new species of flora and fauna are discovered even today in the Himalayas," Nepal's forest and soil conservation minister, Deepak Bohara, said at the release of the report in Katmandu.
Further study of the eastern Himalayas would find far more new species, said Bittu Sahgal, editor of Sanctuary Asia, a wildlife and environment magazine published in India.
"There will be close to 3,000-5,000 species that will be discovered if a systematic study is done over the next five years," he said.
Still, observers say there no reason to believe that the area is immune to the effects of climate change and development.
"While climate change has its impact, which is common to all other such hotspots, human-induced projects such as construction of 100-plus dams in such a fragile and relatively small area is going to worsen the situation further," said Anwarudin Choudhury of The Rhino Foundation in India.
Japan pop star Sakai turned over to prosecutors
The case of the 38-year-old was sent to the Tokyo District Public Prosecutors Office "on suspicion of possessing stimulant drugs," a spokesman for the Tokyo Metropolitan Police Department said.
Prosecutors will decide later whether or not she is to face court.
A minivan carrying Sakai, who has a 10-year-old son, was seen shuttling between a Tokyo police station, where she has been detained since her arrest on Saturday, and the prosecutors' office.
Sakai -- who has enjoyed popularity in China, Taiwan and South Korea and is known for her girl-next-door image -- was seen in television footage looking fixedly downwards in the vehicle's rear seat.
Sakai's husband, pro-surfer Yuichi Takaso, 41, was arrested a week earlier with a bag of methamphetamines in Tokyo's Shibuya entertainment district.
Sakai rushed to the scene to defend him before police discovered the illegal substance in his underwear.
She left the scene saying that she had to tend her school-age son, promising to see police later, but then could not be contacted by telephone or email for the rest of the week.
Police issued an arrest warrant on Friday for her after they reportedly found a small amount of methamphetamines at her house, where she was living separately from her husband.
Sakai made her music debut in 1986 and has until recently appeared in TV commercials for carmaker Toyota.
She has also appeared in a promotional video for Japan's Supreme Court to raise public awareness of a new jury system that was introduced last week.
In 1993, she took part in a celebrity campaign to fight youth drug use.